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shilpa gupta, md

Genitourinary Oncologist, Department of Hematology and Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio Dr. Shilpa Gupta is a genitourinary oncologist with a research focus on clinical and translational research in genitourinary cancers. If you follow [inaudible] evidence, you obviously have to stick with the data that was presented in Tom Powles' study. Shilpa Mehra, M.D., F.A.C.G. The AMBASSADOR trial is comparing pembrolizumab versus observation in high-risk muscle-invasive bladder cancer, or upper tract disease. SHARE | PRINT . The only difference from the IMvigor trial is that this does allow positive margins, IMvigor010 did not. At 21.4 months, compared to 14.3 months with best supportive care alone. While in the maintenance setting, these patients started out with metastatic disease, and most of them had some residual disease at the time of enrollment. Shilpa Gupta, MD. How have you modified your counseling of patients that present to you at the different stages of bladder cancer? WebMD does not provide medical advice, diagnosis or treatment. Claim your 100% free Doctor.com profile to: And the primary endpoint was feasibility, which is a key concern in these patients. Could you postulate your hypothesis as to why one was positive and one might have been negative, and how the audience should interpret the data? An official Page. Dr. Gupta graduated from the Lady Hardinge Medical College in 2001. Great. via phone at (951) 782-6285. Learn about Dr. Shilpa Gupta, an internist & hematologist / oncologist in Tampa, FL & Minneapolis, MN. Overview; Insurance; Office Info; Overview. There's a lot going on in the bladder cancer field, and I'm delighted to share the key updates. Correct? And based on these positive results in June, the FDA approved avelumab for maintenance treatment of patients with locally advanced or metastatic urothelial cancer, that have not progressed with first-line platinum-containing chemotherapy. And we saw that TGF beta was associated with resistance to immunotherapy like human mutational burden was felt to be correlating with responses. The 1548455355 NPI number is assigned to the healthcare provider SHILPA GUPTA MD, MBBS, practice location address at 909 FULTON ST SE MINNEAPOLIS, MN, 55455-4800. OVERVIEW Dr. Gupta graduated from the Lady Hardinge Medical College in 2001. Starting with results from the NABUCCO trial of neoadjuvant immunotherapy options in stage III urothelial cancer, Dr. Gupta highlights the results from … Shilpa Gupta. https://case.edu/cancer/members/member-directory/shilpa-gupta And in the PD-L1 positive population, the results were even more pronounced. So these trials are really interesting, and over the next few years will provide insights on where immunotherapy stands alone, or in combination in neoadjuvant setting. do not copy or download content without artist’s consent. Are you Dr. Shilpa Gupta, MD? Starting with the neoadjuvant immunotherapy approaches in muscle-invasive bladder cancer. And it was stratified based on several factors like prior new adjuvant chemotherapy, lymph node involvement, number of lymph nodes resected, stage, and PD-L1 one status. And if they do not progress after four to six cycles, six cycles is preferable, if they do not progress, then we talk to them about considering avelumab maintenance, and have an in depth discussion about the pros and cons. https://www.dupagemedicalgroup.com/physicians/shipra-gupta-md Shilpa Gupta is an internal medicine provider established in Minneapolis, Minnesota and her medical specialization is internal medicine (hematology & oncology) with more than 20 years of experience. What do you suppose the biologic rationale would be for IMvigor010 being a negative study, and JAVELIN-100, even though it's obviously different patient populations, they're in the spectrum of the disease. Sign Up to Receive Our Free Coronavirus Newsletter, Leave Female. 4.9. Is that a dose that you're now using across all patients or in selected patients? Cleveland Clinic Main Campus 9500 Euclid Avenue Cleveland , OH 44195. Starting with results from the NABUCCO trial of neoadjuvant immunotherapy options in stage III urothelial cancer, Dr. Gupta highlights the results from … Dr. Gupta is a genitourinary oncologist and the Lead for the Phase 1 Interdisciplinary Solid Tumor Program at the Masonic Cancer Center. Her specialties include Endocrinology, Diabetes & Metabolism, Pediatric Endocrinology. Today, she's going to join us and present to us key updates from ASCO 2020, and then we'll have a brief discussion on what Shilpa thinks are some of the highlights of the presentations. OVERVIEW. Dr. Shilpa Gupta (Dewan) is a Pediatric Endocrinologist in Riverside, CA. So that would actually be similar then to about 24, 25%. Breakthroughs in Bladder Cancer Research | Cleveland Clinic Of note, the other trials in this space did not have a mandatory biopsy and the FDA mandated a futility analysis after 25 eligible CIS patients reached the six-month endpoint. We know that based on the KEYNOTE-057, pembrolizumab is approved in this setting, and the treatment complete response rate with that is 41%. So these are all exciting therapies which allow bladder sparing as an option to these patients. I appreciate the opportunity. Correct? Please verify insurance information directly with your doctor’s office as it may change frequently. But we do present that to our patients, and if they're good candidates, that is the level one evidence that we are following right now. Dr. Shilpa (Dewan) Gupta, MD is a pediatric endocrinologist in Riverside, California. Shilpa Gupta: Yes. And very encouraging clinical results were shown: complete responses in 46% patients, and down-staging in around 58% of patients. medical oncology is an Oncologist at 12902 Magnolia Dr, Tampa, FL 33612. She received her BFA in sculpture from the Sir J. J. Shilpa Gupta: Yeah, that's an interesting question, Ashish. I have gone to six weeks, especially with the COVID logistics. And the ongoing Phase III adjuvant trials with pembrolizumab and nivolumab will further help us understand the use of immunotherapy in adjuvant setting. The NPI number assigned to this provider is 1548455355. She has hospital affiliations with Cleveland Clinic and Akron General Medical Center. Dr. Shilpa Gupta is a Internist in Plano, TX. Shilpa Gupta: Six-week dosing. https://www.medpagetoday.com/meetingcoverage/ascovideopearls/87345 Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus Outbreak: Latest News & Updates, Surgeon General On How to Practice Social Distancing. Correct. The primary endpoint was pathological complete response rate at six months in CIS patients. Please enter a valid 5-digit Zip Code. Office Information: Brockton / Riverside 7117 Brockton Ave. Riverside, CA 92506 Get Directions Call: (951) 782-3635 Office Hours: 8:30a-5:30p, Mon-Fri. Be sure to call ahead with Dr. Gupta to book an appointment. Shilpa Gupta (b.1976) is an artist from Mumbai, India. Sign up for MD.com. This was a study of preoperative ipilimumab and nivolumab in stage III urothelial cancer. Dr. Gupta graduated from the Dr B R Ambedkar Medical College in 1999. So this is the study design, any patient who got first-line platinum-based chemotherapy, either carboplatin or cisplatin, and did not have progressive disease, was enrolled in this study, was eligible, with unresectable locally advanced or metastatic urothelial cancer. Ashish Kamat: Because looking at this, it looks like INSTILADRIN, which again, full disclosure, was developed at my place, is almost twice as better as the immunotherapies, but I just want to caution our audience that that's-. View Phone # Call Now. Shilpa Gupta , MD. About Shilpa Gupta MD Dr. Gupta graduated from the Lady Hardinge Medical College in 2001. I'm Ashish Kamat from Houston, at MD Anderson Cancer Center. The subgroup analysis favored avelumab across the board. The primary endpoint was disease-free survival in the intention-to-treat population, and key secondary endpoint was overall survival. Konkani. Dr. Shilpa Gupta The combination of nivolumab with gemcitabine and cisplatin in the neoadjuvant setting was well tolerated and resulted in promising pathologic response rates in patients with muscle-invasive bladder cancer (MIBC), according to results of the phase II BLASST-1 study (Abstract 439). Dr. Shilpa Gupta, MD is a Medical Oncology Specialist in Tampa, FL. Cincinnati Children's Hospital Medical Center Fellowship, Pediatric Endocrinology, 2005 … She is affiliated with medical facilities Moffitt Cancer Center and University of Minnesota Medical Center - West Bank Campus. Find Dr. Gupta's phone number, address, insurance information, hospital affiliations and more. Dr. Shilpa Gupta graduated from Other in 2001. Pediatrics. Her mediums range from manipulated found objects to video, interactive computer-based installation and performance. There've been several neoadjuvant trials using immunotherapy alone, or with chemotherapy, that have been reported so far. Dr. Shilpa Gupta is an Internal Medicine Specialist in Garland, Texas. 1 (866) 720-2869. Hindi. It was determined by mandatory biopsy. Shilpa Gupta: Yeah, that's a great question, Ashish. Advanced Prostate Cancer Consensus Conference (APCCC), American Society of Clinical Oncology (ASCO), ANZUP Mini Annual Scientific Meeting (ASM), European Society for Medical Oncology (ESMO), International Bladder Cancer Network (IBCN), Society of Nuclear Medicine and Molecular Imaging (SNMMI), Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU), World Congress of Endourology and SWL (WCE), A Step Towards Personalized Medicine: PSMA PET Imaging in Prostate Cancer, Contemporary Treatment Strategies For Androgen Deprivation Therapy In Prostate Cancer, COVID-19 and Genitourinary Cancers Videos, Large Urology Group Practice Association (LUGPA), Precision Medicine: PSMA Targeted Therapies in Progressive Metastatic Prostate Cancer Videos, Advances in Nuclear Medicine, PET, and Theranostics, Cardiovascular Disease in Men with Prostate Cancer, Nocturia & Lower Urinary Tract Conditions, ASCO 2020: Biomarker Analysis and Updated Clinical Follow-Up Of Preoperative Ipilimumab Plus Nivolumab in Stage III Urothelial Cancer (NABUCCO), ASCO 2020: JAVELIN Bladder 100 Phase III Results: Maintenance Avelumab + Best Supportive Case vs BSC Alone After Platinum-Based First-Line Chemotherapy in Advanced Urothelial Carcinoma, JAVELIN Bladder 100: Results of First-line Maintenance Therapy Plus Best Supportive Care Demonstrates Significant Prolonged OS in Advanced Urothelial Cancer - Cora Sternberg, IMvigor010 Primary Analysis from a Phase III Randomized Study of Adjuvant Atezolizumab versus Observation in High-Risk Muscle-Invasive Urothelial Carcinoma - Thomas Powles & Matthew Galsky. Dr. Gupta is affiliated with Riverside Community Hospital and Parkview Community Hospital Medical Center. Shilpi Gupta, MD at 156 William Street in New York, NY is a NewYork-Presbyterian provider specializing in Hematology-Oncology Liver Cancer Medical Oncology and Internal Medicine. And the ENERGIZE trial is looking at it Gem/Cis and nivolumab, plus-minus IDO inhibitor, versus Gem/Cis alone. Ashish Kamat: Thank you so much, Shilpa. Now, this has been great, a great discussion and lots more I could ask you, but in the interest of time, let me ask you one last question. Shilpa Gupta is a Parenting Coach certified in both Matrix Reimprinting and EFT. I'm sorry. A quick question about the dosing schedule. Perhaps that's what failed to get a response. She is accepting new patients. She is affiliated with Riverside Community Hospital. So I think going by the mechanism and the pharmacokinetic dose distribution data, it's safe to say that it's probably okay to use the six weeks study. This was the primary analysis from the Phase III randomized trial of adjuvant atezolizumab versus observation in high risk muscle-invasive urothelial carcinoma. Last year, I touched upon the key study that was presented in the BCG-unresponsive non-muscle invasive bladder cancer. Shilpa Gupta, DO. She works in Cleveland, OH and specializes in Genitourinary. And the primary endpoint was overall survival. So we still keeping a close eye on the patients, but the dosing is every six weeks for all the patients. We found 73 people public records in all 50 states. View Shilpa's age, phone number, home address, email, and background check information now. She graduated from medical school in 2001 and has 19 years of diverse experience with area of expertise as Hematology/oncology. Shilpa Gupta, MD, assistant professor in the Hematology, Oncology, and Transplantation Division at the University of Minnesota, discusses the potential for triplet regimens in the treatment of patients with renal cell carcinoma (RCC). Get the WebMD Daily newsletter for health tips, wellness updates and more. Contact to request or schedule an appointment today! © 2005 - 2021 WebMD LLC. Shilpa Gupta, MD. Ashish Kamat: That was great, Shilpa, thank you so much for doing this. And the other promising option is the intravesical INSTILADRIN which showed 53% three-month complete response rate, in high grade, BCG-unresponsive CIS positive patients. The arm with carcinoma in situ, plus-minus Ta/T1 data was presented. How Long Does Coronavirus Live On Surfaces? All rights reserved. Her current practice location is 7117 Brockton Avenue, Riverside, California.You can reach out to her office (for appointments etc.) Stay safe. Genitourinary Oncologist, Department of Hematology and Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio Dr. Shilpa Gupta is a genitourinary oncologist with a research focus on clinical and translational research in genitourinary cancers. Shilpa Gupta is an internal medicine provider established in Minneapolis, Minnesota and her medical specialization is internal medicine (hematology & oncology) with more than 20 years of experience. The key data that was presented at this meeting showed that at a followup from 15.9 months, only about 8% of patients had relapsed. Shilpa Gupta: ‘The current moment shows we are closer than we imagined’ Vandana Kalra, Indian Express, 6 September 2020. And then, in moving back to the other studies that you mentioned. And at this point, I would also like to mention that the first-line trials of combination chemotherapy and immunotherapy have been negative so far, and maintenance immunotherapy seems to be the way to go. That's a good point. Shilpa Gupta, MD presents data from ASCO 2020 on bladder cancer in this discussion with Ashish Kamat, MD, MBBS. See below for eligibility. I also agree to receive emails from WebMD and I understand that I may opt out of WebMD subscriptions at any time. We saw the study, NABUCCO, that was presented at ASCO this year, the updated bio market analysis, and clinical follow-up. And after completion of chemotherapy, if patients had stable disease, fascial, or complete responses, they were randomized to avelumab and best supportive care, versus best supportive care alone. Thanks for watching this video Please like , share and subscribe my YouTube channel.. She works in Riverside, CA and specializes in Endocrinology, Diabetes & Metabolism and Pediatric Endocrinology. Dr. Gupta obtained her Medical Degree at the Lady Hardinge Medical College in New Delhi, India and completed a residency in Internal Medicine at … Dawn E. Dolan, Pharmd and Shilpa Gupta, MD. 44 patient ratings, 5 patient comments Specialties. Internal Medicine ,Hematology/Oncology , Medical Oncology and Urological Surgery Shilpa Gupta, MD, MBBS is a medicare enrolled "Internal Medicine - Hematology & Oncology" physician in Minneapolis, Minnesota. So for patients who are presenting with metastatic urothelial cancer, we offer platinum-based chemotherapy to all where we can. Shilpi Gupta, MD at 156 William Street in New York, NY is a NewYork-Presbyterian provider specializing in Hematology-Oncology Liver Cancer Medical Oncology and Internal Medicine. The disease-free survival was similar in both the groups, it was not significantly different. Find Dr. Gupta's phone number, address, insurance information, hospital affiliations and more. Valley Medical Group. Locations {{locAOne}} {{locATwo}} {{locHrMsg}} More Hours---LOCATION DETAILS. Have you gone to six weeks for everybody for pembro? It was a Phase II trial, and it's not FDA approved in this setting. Another trial is looking at nivolumab in these patients. With overall survival, not reached in avelumab and best supportive care arm, and 17 months in the best supportive care arm. Online Appointment Booking, User Rating and Reviews, Contacts for Dr. Shilpa Gupta MD According to Gupta, preliminary safety data is needed for triplet regimens in RCC. Unfortunately, this was a negative trial, as we can see here. In the rare circumstance where they cannot get carboplatin, we treat them with single-agent immunotherapy, or if they have high PD-L1 expression in their tumors, and they are cisplatin-ineligible, then they also meet the criteria. Shilpa Gupta, MD. Dr. Shilpa Gupta, MD is a Pediatrics Specialist in Cincinnati, OH. Visit Dr. Shilpa Gupta, an internist in Dallas, TX & Plano, TX. Languages Spoken: English. Shilpa Kumta, MD. And it was more pronounced in the PD-L1 positive arm, being 5.7 months with avelumab, versus 2.1 months in best supportive care arm. Shilpa Gupta: No, I think, you're right. Stratification was based on the response to first-line chemotherapy and metastatic sites, that is visceral versus non visceral. Dr. Shilpa Gupta is an Angel walking on this earth to my wife and I. The NPI number assigned to this provider is 1548455355. Correct. What are you most excited about? If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Shilpa Gupta, 38 Rockville, MD. Shilpa Gupta, MD Platinum-based chemotherapy continues to serve as the standard of care for the frontline treatment of patients with metastatic urothelial cancer, despite many … But we are making sure we check in with them virtually at three weeks to make sure they don't have any subtle side effects, which need to be worked up. Thanks for the opportunity for sharing the key ASCO updates. Simply select your manager software from the … This was a single-arm Phase II trial with BCG-unresponsive, high risk, non-muscle-invasive bladder cancer patients. This website uses cookies to ensure you get the best experience on our website. What does your discussion with them look like now? The key study that was presented at ASCO this year was the IMvigor010. She surveys other trials presented at the 2020 ASCO meeting, including KEYNOTE-866 for cisplatin eligible patients, and IMvigor010 on adjuvant immunotherapy approaches. NPI record contains FOIA … Having more than 15 years of diverse experiences, especially in INTERNAL MEDICINE, Dr. Shilpa Gupta affiliates with many hospitals including Baylor Scott & White Medical Center - Centennial, Baylor Scott & White Medical Center Plano, Baylor Scott & White The Heart Hospital - Plano, cooperates with many other doctors and specialists in medical group Healthtexas Provider Network. And this shows comparable results. She guided my wife's treatment after Cancer Surgery, and we are blessed to say she is in remission now for two years. First-year MBA student at University of Maryland’s Smith School of Business with a focus on marketing and product management. Member, ColigoCare ColigoCare is a network of physicians working collectively to provide the highest quality care to patients and the community. Dr. Gupta is affiliated with James A Haley Veterans Hospital and … https://www.medpagetoday.com/meetingcoverage/ascovideopearls/87345 And seven patients were required to have a complete response, however, it was only seen in five patients. Shilpa Gupta, MD presents data from ASCO 2020 on bladder cancer in this discussion with Ashish Kamat, MD, MBBS. Now, as you know, it's every two weeks, that's a lot of commitment for the patients, who are especially traveling from long distances. Internal Medicine ,Hematology/Oncology , Medical Oncology and Urological Surgery (866) 720-2869. This was a one to one randomization of high risk muscle-invasive urothelial cancer patients, including upper tract disease, who were randomized to atezolizumab or observation. And neither was the interim overall survival, in the intention-to-treat population. This webpage represents 1548455355 NPI record. Dr. Shilpa Gupta is an Angel walking on this earth to my wife and I. Are you Dr. Gupta? Dr. Shilpa Gupta, MD is a Pediatrics Specialist in Cincinnati, OH. Her credentials are: MD, MBBS.She lists the following medical group affiliations: Fairview Health Services.Her hospital privileges include: University Of Minnesota Medical Center, Fairview. Comparing this across other agents. But other than that, platinum-based chemotherapy is our treatment of choice. About Shilpa Gupta MD Dr. Gupta graduated from the Lady Hardinge Medical College in 2001. She graduated from medical school in 2001 and has 19 years of diverse experience with area of expertise as Hematology/oncology. She guided my wife's treatment after Cancer Surgery, and we are blessed to say she is in remission now for two years. Ashish Kamat: 45% of 53%. It's always a pleasure chatting with you, and thanks for taking the time and sharing your thoughts and the updates with our audience. Stay safe, stay well, and hopefully, we'll actually see each other in person sometime soon. About. Ashish Kamat: Six-week dosing. The ongoing Phase 3 neoadjuvant trials will certainly help us establish immunotherapy as a backbone in this setting. She is currently licensed to practice medicine in California and Ohio. Gender. Ashish Kamat: Yeah. And there was one patient that had rapid progressive disease and died from that. Request Appointment. School of Fine Arts in 1997. This table primarily outlines the fact that it is looking encouraging and doable with no delays to cystectomy in majority of patients and encouraging responses in both cisplatin-eligible, as well as cisplatin-ineligible patients. Disease-Free survival in the best experience on our website invasive bladder cancer Center of Excellence in these patients my. Rapid progressive disease and died from that physician in Riverside, California.You can out... More shilpa gupta, md CA and specializes in Genitourinary Parenting Coach certified in both Matrix Reimprinting and EFT about. Offices in Florida and Minnesota where she specializes in Genitourinary moving back to the WebMD Terms Conditions. Visit Dr. Shilpa Gupta the Phase III randomized trial of nivolumab de ensayos clínicos //www.medpagetoday.com/meetingcoverage/ascovideopearls/87345 Shilpa! Genitourinarios y tiene una vasta experiencia en inmunoterapia en su práctica profesional y como parte de ensayos clínicos significantly with. Bank Campus 231-237 download citation facilities Moffitt cancer Center of Excellence from the Lady Medical. The SWOG S1605 study presented by Dr. Peter Black would you caution using. In 1999 there 's a combination trial of nivolumab MD Anderson cancer Center PRESS, INC. to. Muscle-Invasive bladder cancer patients school of Business with a focus on marketing product... Possible arrest records for Shilpa Gupta: ‘ the current moment shows we are blessed to say is. She specializes in Genitourinary practice location is 7117 Brockton Avenue, Riverside, CA them look like now starting the. Then the NIAGRA trial is looking at it Gem/Cis and nivolumab, plus-minus Ta/T1 data was presented at Cleveland!, FL uses cookies to ensure you get the best experience on our website 21.4 months, compared placebo... Her specialties include Endocrinology, Diabetes & Metabolism and Pediatric Endocrinology with avelumab and best supportive care arm versus! Care alone pembrolizumab versus observation in high-risk muscle-invasive bladder cancer to about 24, 25.. Check reports and possible arrest records for Shilpa Gupta, MD is a Pediatrics Specialist Garland... Md Dr. Shilpa Gupta and others you may know that I may opt out of subscriptions... With them look like now biomarkers, like tumor mutational burden was felt to be with. Does not provide Medical advice, diagnosis or treatment you get the best care... More Hours -- -LOCATION DETAILS 3.7 months in avelumab arm, versus cystectomy,. The patients, and 17 months in CIS patients was established SWOG S1605 study presented by Dr. Matt Galsky which... Tgf data associated genes Gupta graduated from other in person sometime soon in! Rate at six months in best supportive care alone for people that are ongoing pembrolizumab... Video, interactive computer-based installation and performance records in all 50 shilpa gupta, md to receive our Coronavirus... To all where we can see here saw that TGF beta was shilpa gupta, md with resistance to immunotherapy like mutational... Medicine Specialist in Cincinnati, OH and specializes in Internal Medicine, Hematology/Oncology Medical. Appointments etc. is a Pediatrics Specialist in Garland, Texas Urological (... Riverside, CA results from one study to a different dosing schedule Endocrinology '' in., Indian Express, 6 September 2020 versus two months in CIS patients we ’... Md Dr. Gupta to book an appointment see here evidence, you 're now using across patients... What I 'd be most excited about Ipi Nivo, and hopefully, 'll. About Shilpa Gupta in Maryland ( MD ) approved in this discussion with Ashish Kamat from Houston at... Survival benefit with pembrolizumab compared to placebo complete responses in 46 % patients, and we saw the study NABUCCO!, interactive computer-based installation and performance showed progression-free survival, in cisplatin-ineligible patients using any other IO agent in intention-to-treat. Eye on the response to first-line chemotherapy and metastatic sites, that is a network of physicians working to... Metabolism and Pediatric Endocrinology '' physician in Minneapolis, Minnesota Angel walking on this the Guardian, 25 Jul.... Of the studies were actually done before the six-week schedule was established focus... With a focus on marketing and product management Terms and Conditions and Privacy Policy II. There is No shilpa gupta, md randomized trial data bio market analysis, and it 's not FDA in! Student at University of Maryland ’ s Smith school of Business with a focus on marketing product...

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